What is the primary function of basophils in the immune system?

Basophils play a crucial role in the immune system primarily through the release of histamines and other mediators that are involved in inflammatory responses. When they encounter allergens or pathogens, basophils release histamines, which contribute to the inflammatory process by increasing blood flow and the permeability of blood vessels. This allows immune cells to access tissues where they are needed to fight infection or respond to allergens.

Histamines also play a significant role in allergy and defense mechanisms, contributing to symptoms such as swelling, redness, and itching during allergic reactions. This function is essential, as it helps to initiate the proper immune response to potential threats, such as infections and allergies, facilitating a quick response to these challenges.

While phagocytosis of pathogens, antibody production, and activation of T cells are vital functions of other immune cells like macrophages, B cells, and T cells, respectively, these functions are not primary to the role of basophils. Their specialization lies in the release of histamines and participation in hypersensitivity reactions, distinguishing them from other cell types in the immune system.