What type of test helps to determine the malignancy of a neoplasm?

A biopsy is a medical procedure that involves taking a small sample of tissue from a neoplasm, which is an abnormal growth of tissue, to be examined under a microscope. This examination is crucial for determining whether the neoplasm is benign (non-cancerous) or malignant (cancerous). The histopathological analysis of the biopsy specimen provides definitive information regarding the cellular characteristics of the neoplasm, which may include the presence of cancer cells, their type, and grade.

Unlike a blood test, which may provide information about markers related to cancer but cannot definitively diagnose malignancy, or imaging tests like ultrasound and X-ray, which can help visualize the structure of a neoplasm but do not provide cellular information, a biopsy directly involves the analysis of tissue. Therefore, it is the most reliable method for diagnosing malignancy.

In summary, a biopsy is the gold standard for assessing the nature of a neoplasm, making it the correct choice for determining malignancy.