Which mood disorder may involve extreme fatigue and disinterest in daily activities?

Major depressive disorder is characterized by a range of emotional and physical symptoms, including extreme fatigue and a lack of interest or pleasure in daily activities. Individuals diagnosed with this disorder may experience persistent feelings of sadness, hopelessness, and a significant loss of energy that can affect their ability to perform routine tasks, engage socially, or maintain their usual quality of life. This profound disinterest can lead to significant impairment in functioning across various domains, such as work, school, or personal relationships, making it a core symptom of the disorder.

The other conditions mentioned present with different symptoms and may involve various aspects of mental distress, but they do not primarily manifest through the severe fatigue and anhedonia (loss of interest) that define major depressive disorder.